Tag Archives: antioxidants

Flavonoids

Flavonoids are powerful antioxidants, and sturdy defenders against heart disease and cancer. See also my article titled: Antioxidants in green leafy vegetables
Like carotenoids, flavonoids add color – specifically red, yellow, blue and shades of brown
to the foods we eat and drink.
Present mostly in apples, celery, cocoa, (dark chocolate), cranberries, grapes, broccoli, endive, onions, green and black teas, and red wines.

But experts are beginning to discover that these compounds are doing more.
Some flavonoids make the linings of blood vessels more supple, lowering blood pressure and protecting against a buildup of heart- threatening plague. In one study, grape juice and
chocolate had this effect. Flavovoids also act like Teflon coating for the millions of tiny disks in your blood called platelets. They keep the platelets from clumbing together in the bloodstream and forming clots, which helps prevent heart attacks and stroke.

A recent study at the Harvard Medical School lab has found that one magical flavonoid found in wine and grapes: resveratrol, also lowers blood sugar levels and boosts liver function. In fact, in a group of lucky mice, it increased longevity by 31%.
In one study at the university of Virginia, resveratrol – found in grape skins, raspberries,
mulberries, and peanuts – literally starved cancer cells by interfering with a protein called
nuclear factor-kappa B, that helps food them.

In one Dutch study that examined the eating habits of 800 men, aged between 65 and 84,
researchers found that those who got the least flavonoids in their diets, were 32% more
likely to die from heart attacks than those who ate the most. It didn’t take many flavonoids
to get the benefits. The high-flavonoid group had the equivalent of 4 cops of black tea,
a half cup of apple, and 1//8 cup of onions per day.

When it comes to cancer prevention, flavonoids may help out by influencing cel-signaling
pathways – the way cells turn genes on and off in order to perform thousands of everyday
maintenance activities. Flavonoids may help turn on genes that stop cancer cells from
dividing or invading healthy tissues, or even help activate genes that make cancer cells
commit suicide, say experts from the Linus Pauling Research Institute at Oregon State
University in Corvallis.

In a recent study at the University of California, Los Angeles, those prostate-cancer
survivors who drank 8 ounces of pomegranate juice daily, increased by nearly 4 times
the period during which their PSA levels (prostate specific antigens) a cancer biomaker,
stayed constant. The study even surprised the researchers, who say that the combination
of flavonoids, anti-inflammatory compounds, and antioxidants in pomegranate juice
may be responsible.

Antioxidants in Green Leafy Vegetables

Antioxidants you find in the red of tomatoes and the yellow plant pigments in carrots  are called carotenoids. You also find them in green leafy vegetables They belong to the family of phytonutrients. See also my article: Phytonutrients, compounds from the garden.
These carotenoids are powerful antioxidants to fight against heart disease and certain forms of cancer.

Research has shown promising results from a number of carotenoids, particularly lycopene
(also found in tomatoes), lutein (found in vegetables such as spinach and kale), and
zeaxanthin ( found in dark green leafy vegetables). All three play a powerful role as antioxidants  in cancer prevention.

Researchers in the Tufts University Carotenoids Health Laboratory say: “Skipping fruits &
vegetables is part of the classic “profile” of people who develop cancers of the head and
neck, but that increasing your intake of these antioxidants rich products may cut your risk for recurrence of these cancers.

In one study, researchers found that people in northern Italy who ate seven or more
servings  of raw tomatoes every week  had a 60% lower change of developing colon, rectal,
and stomach cancer than those who only ate two servings or less.

German researchers have found that cooked tomato products containing some oil –
such as spaghetti sauce – boost lycopene absorption dramatically. They believe that
heating  and crushing releases more lycopene, and that the body  needs substances in
oil to  help better absorption.

Harvard researchers, looking at green leafy vegetables, especially spinach, had quite
an eye-opener. They found that people eating the most lutein and zeaxanthin – which
are two carotenoids , powerful antioxidants found in these vegetables – had a 43% lower risk of macular degeneration  than those eating the least.
Macular degeneration is the leading cause of irreversible vision loss in people  over 50.
Lutein and zeaxanthin concentrate in your retinas and protect them by absorbing
harmful blue-wavelength light found in sunshine.

Other members of the Phytonutrients are: flavonoids, indoles,  lignans, monoterpenes, saponins, organosulfur – and phenolic compounds, which are all powerful antioxidants,
I will discuss in future articles.  If you like to know more about plant-based nutrition,
I refer to : Nutrition studies.org

Phytonutrients: compounds from the Garden for good Health

Within plant foods are thousands of compounds that are taking the diet-disease connection to an exciting new level.Science call these compounds phytochemicals or phytonutrients, that means chemicals or nutrients found in plants.

They are there to help our garden survive and strive.
Potent sulfur compounds in garlic and unions, for instance, act as bug repellents to keep
the vegetables healthy. Other compounds protect plants from bacteria, viruses, and other
natural enemies. When we eat plant foods, these compounds protect us, too – not from
bugs but from the forces that wreak havoc in our bodies.

We have known for many years that we need vitamins and minerals from our food
to maintain good health, and to prevent malnutrition and diseases such as rickets and scurvy. But research revealed that the essential nutrients we all know, such as vitamin A and E, are just the beginning. See also my page: health-and-fitness

Most likely some of these previously unknown compounds will fight not only deficiency-type diseases such as anemia, but also age-related illnesses such as arthritis, cancer, diabetes, heart disease, high blood pressure, and stroke.

And the research has only begun. Scientists are discovering more phytochemicals all
the time and also ways in which theses compounds fight disease.

Neutralizing Free Radicals

Each member of the large family of phytonutrients work indifferent ways.
However, their most common weapons against disease appear to be their antioxidant
abilities.

Every day your body is under attack by harmful substances known as free radicals.
These are oxygen molecules who have lost an electron, due to pollution, sunlight,
stress, smoking, physical activity, and sunlight. As they attempt to regain there
missing electrons, they travel through your body and stealing electrons from your
body cells and sometimes from your DNA wherever they can.

Unless this chain reaction is stopped, the result is huge numbers of damaged
molecules and, over time, damage and disease.

For example, cholesterol is a useful and helpful substance. But when cholesterol
molecules are damaged by free radicals, they start to stick to the lining of
artery walls, causing hardened arteries and heart disease.

Another example: When free radicals attack molecules in the DNA of your body cells,
the genetic blueprint that tells your cells how to function, is damaged.
This can spark dangerous cell changes that lead to cancer and other diseases.
Even the aging process itself, scientists believe,is caused by free-radical damage.
The powerful antioxidants of phytonutrients in plants can literally save your life.

Essentially, they step between the free radicals and your body’s cells, offering up
their own electrons. When free radicals grab these “free” electrons, they become
stable again and do no further damage. Most phytonutrients are potent antioxidants.

Eliminating Toxic Wastes

Another way phytonutrients keep us healthy is by neutrolizing and flushing
toxic chemicals from our bodies before they make us sick. They do this by
manipulating enzymes known as phase-1 and phase-2 enzymes, explains Gary Stoner, PhD, professor and cancer researcher at Ohio State University in Columbus.
Phase-1 enzymes are like double agents. They are created by your body and are

important for normal cell function. But they also have the ability to work
against you. When cancer-causing toxins enter your system, phase-1 enzymes
help make them active. Phase-2 enzymes, on the other hand, are real good guys.
They seek out carcinogens and detoxify them before they can do damage.

When you eat broccoli or other vegetables, some of the phytoneutrients begin
stomping out the enemy phase-1 enzymes while increasing the production of
helper phase-2 enzymes. This process helps neutralize various cancer-causing
toxins that naturally accumulate in your body.

Regulating Hormones

A third way in which phytoneutrients fend off disease is by keeping certain
hormones – most notably the female sex hormone estrogen – at healthy levels.
Estrogen is “good news” and “bad news” kind of hormone. When it’s produced at
normal levels, it helps control everything, from menstruation to childbirth.
At the same time, it helps keep artery-clogging cholesterol in check, thus
preventing heart disease. When estrogen levels rise, however, they can fuel
hormone-stimulated cancers like breast cancer and cancer of the ovaries,
according to researchers.

There are several ways in which phytoneutrients keep estrogen at proper levels.
For example, a class of phytonutrients called isoflavones is extremely similar

to natural estrogen. When we eat foods containing isoflavones, these faux
hormones bind to the body’s estrogen receptors, leaving the real hormone with
nowhere to go but out.

Although estrogen is often referred to as if it were one hormone, in fact
there are different forms. One kind of estrogen, called 16-alpha-hydroxyestrone,
has been linked to breast cancer. Another form, 2-hydroxyestrone, appears to
be harmless. Certain phytonutrients are able to increase levels of the harmless form of estrogen, while decreasing levels of the dangerous kind.

Eating Your Medicine

From the previously mentioned facts it shows that phytonutrients bring in a diversity of
powerful defences. As a matter of fact, their potential is staggering.
Scientists forecast that in the near future these compounds will be used for treating disease in the hospital and for prevention at home, as was the case with vitamins and minerals.


Till then, scientists emphases that the only way to get the phytonutrients your body needs
is to eat them as Mother Nature brings them. That means eating fruits and vegetables at 
least nine servings per day for good health.
Scientists learn new things every day about this huge class of compounds that the glass
of orange juice contains that you have for breakfast in the morning and in the site salad
at lunchtime.

If you like to know more about plant-based nutrition, visit: http://nutritionstudies.org/

Problems Concerning the Eyes

Cataract surgery is most common for people over the age
of sixty In the US, eye surgeons perform 1.3 million cataract
operations every year for a total cost of US $3.5 billion.

The lens of the eye collects and focus light on the retina.
It is important for the lens to stay clear throughout our lifetime,
In order to function properly. As we age, various components
of the lens may get damaged, leading to cataracts.

Medical research has proven that supply of sufficient anti-
oxidants at an early age can prevent cataract formation.
Antioxidants are needed to combat against free radicals,
due to ultraviolet sunlight.

In particular the fluid around the lens of the eye has to be
protected by antioxidants against oxidative damage.
The most important antioxidant is vitamin C, which is found
in high concentration around the lens, as well as vitamin E,
alpha-lipoic acid and beta-carotine.

A study showed that consuming vitamins in supplementation
protects the eye and decrease the risk of developing
cataracts by 50%. There is sufficient evidence that taking
antioxidants is an inexpensive way to decrease cataract
formation.

Another problem concerning the eye is macular degeneration.
It is the leading cause of blindness in people over the age of
sixty.

This is the decay of an important part of the retina called
macula. This is the area, which deals with central vision,
where the greatest concentration of photoreceptors are located.

We recoqnize wet and dry forms. Ninety percent of the cases
represent the dry form, in which central vision gradually
reduces and may proceed to the wet form for the remaining
ten percent.

There is currently no treatment available for the dry form.
The wet form can be treated via laser photocoagulation,
by which new vessel formation can be slowed down, which
causes swelling and bleeding into the retina.
Blindness usually follows rather quickly.

Theories suggest that light entering the eye and focused on
the macula of the retina causes significant free-radical
production in the outer aspect of the photoreceptors.

If there are no sufficient antioxidants available to the
photoreceptors, lipofuscin formation, a toxic substance,
within the retinal pigment epithelium, causes more oxidation
damage to the retina and research believe it is actually
the cause of damage and destruction of these sensitive
photoreceptors.

Lipofuscin accumulate in the pigment epithelium cells and
are eventually excreted in the form of drusen, which is one
of the first indications of macular degeneration development.

The development of drusen separates the photoreceptors
of the eye from its blood supply and causes an area of
blindness.

High-energy ultraviolet light and visible blue light are in
particular responsible for the production of free radicals
in the retina of the eye.

Our natural antioxidant defence system that protects us from
this free radical damage, declines when we get older.
Macular degeneration is characterised by low levels of zinc,
selinium, vitamin C, vitamin E and carotenoid.

High levels of carotenoids, called lutein and zeaxanthine,
absorb the blue light portion of visible light, that can damage
the lens and he retina of the eye. They are strong antioxidants
and are found in corn and leafy green vegetables.

CoQ10 can also play a part in reducing the oxidative damage
caused by free radicals.

Glutathione, which is a very potent antioxidant found within
every cell of our body, is in particular critical within the lens of
our eye and the pigment and the photoreceptor cells of the
retina. The level of glutathione declines when we get older.

Glutathione peroxidase is one of the natural antioxidant
defencesystems that our body creates. The nutrients needed
for the body to make its own defense are selinium, vitamin B6,
N-acetyl-L-cysteine and niacin.

Vitamin C and alpha-lipoic acid have the ability to regenerate
glutathione. Zinc is important for the function of our catalase
antioxidant defense system and selinium is necessary for the
glutathione peroidase system and both are important to
combat free radicals produced in the eye.

As we get older, the lens of our eyes allows more ultraviolet
light through and no longer protects the retina from damage
of ultraviolet light. A good quality pair of sunglasses that
block all UV light are important.

Without any doubt, the underlying cause of cataracts and
macular degeneration is oxidative stress.
Consequently, we can’t be too agressive in our
supplementation plan.

Mushrooms for a long Life

The longest lived people are those following the traditional Mediterranean or Japanese diet, and mushrooms feature and have a place in both diets.

Mushrooms have a range of essential nutrients, such as B vitamins and the antioxidant mineral selenium.
Mushrooms have many other antioxidants. One in particular, ergothioneine, is found mainly in mushrooms among non-animal food sources.

Ergothioneine has its own blood transporter, indicating that it is very important for human health.
To achieve a long and healthy life, mushrooms have a clear role in a balanced healthy diet.

– See more at: http://www.powerofmushrooms.com.au/health-nutrition/health-nutrition/long-life/#sthash.l30ukV1E.dpuf